'Who's the Boss' and 'Charmed' star, Alyssa Milano is set to star in ABC's remake of 'Mistresses,' a British female-driven drama about the complex love lives of four friends.  Also starring in the series is 'LOST's' Yunjin Kim, 'Rochelle Aytes, most recently appearing in ABC's disastrous, 'Work It,' and Jes Macallan, whose had stints on 'Justified' and 'Shameless.' 'Glee's' Cory Monteith is also signed on.

Milano will play Savannah, a workaholic lawyer with a husband at home who's eager to start a family and a handsome partner at the office who she spends many late nights with. The character's name in the original series, Siobhan, was apparently too Celtic for ABC.

The role should feel natural to Milano, who played a lawyer in the ill-fated ABC sitcom, 'Romantically Challenged.' 'Mistresses' is set to premiere this summer on ABC.