Scott Weidemeyer (Sam Eidson) is an antisocial curmudgeon who lives with his grandmother and spends his entire week looking forward to that one night when he plays Dungeons & Dragons with his four nerd buddies. For a powerless guy like Scott, who works as a donut store delivery boy, D&D is the ultimate power fantasy: as the Game Master of the group, he creates elaborate storylines and manipulates the lives of dozens of characters. It's the place where someone who has no control over his life gets to feel in control for a change.
The very funny and very wise 'Zero Charisma' is what happens when that refuge from the real world comes under attack. When Scott's D&D group loses one of its members, he finds a replacement at the local RPG store: Miles (Garrett Graham), who, as it turns out belongs to a new breed of geek. He knows 'Star Trek' and 'Star Wars,' but he has a girlfriend. His website, the oxymoronically titled GeekChic.com, gets hundreds of thousands of hits a day. He drinks and throws parties (that don't involve tabletop games). For a nerd, he actually seems kind of... cool. And his arrival in the game throws it into chaos. Scott may be the Game Master but he finds himself increasingly marginalized as his buddies look more and more to Miles for guidance, advice and friendship.