Though we'll have to wait until September 29 for the full premiere of Showtime's sinfully buzzworthy new series 'Masters of Sex,' it seems the premium cable channel just couldn't wait to show it all off. The first full trailer for the Michael Sheen-Lizzy Caplan serial has arrived, and you might want to keep a handkerchief handy for some serious monocle-defogging.

Starring Michael Sheen (‘Twilight‘) and Lizzy Caplan (‘Party Down’), ‘Masters of Sex’ follows two famous, real-life human sexuality research pioneers of the 1960s, the aforementioned William Masters and Virginia Johnson, chronicling the duo’s unconventional lives moving from a St. Louis teaching hospital to Johnny Carson and the cover of Time Magazine. The series is adapted from Thomas Maier’s book ‘Masters of Sex: The Life and Times of William Masters and Virginia Johnson, The Couple Who Taught America How To Love.’

As you can imagine, work might not be the best place to watch the full three-minute spot for the series. Meanwhile, among the recurring cast are ‘Bridesmaids’ star Wendi McLendon-Covey, Allison Janney, Beau Bridges and ‘Justified‘ Emmy-winner Margo Martindale, the latter two of whom can also be seen on the CBS fall comedy ‘The Millers.’

Come check out the full 'Masters of Sex' trailer above, and tell us if you'll tune in after the 'Homeland' season 3 premiere on September 29!

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