Cinematographer Wally Pfister is gearing up for 'Transcendence,' his directorial debut that stars Johnny Depp in the lead -- but which talented actress will take the female lead by his side?

Deadline reports that casting is well underway for Wally Pfister's 'Transcendence,' the cinematographer's directorial debut about a scientist (Johnny Depp) whose brain is uploaded into a supercomputer by a female scientist named Evelyn after his death. The project is obviously in heavy sci-fi territory, and given Pfister's incredible work with Christopher Nolan on films like 'Inception' and 'The Dark Knight,' we're excited to see the visuals he cooks up with this one.

As for the role of Evelyn, it's being reported that the studios currently have the field narrowed down to three choices for leading lady: Emily Blunt, who was most recently seen in the summer sci-fi action pic 'Looper'; Rooney Mara, who is currently shooting the unnamed Terence Malick project with Ryan Gosling, Natalie Portman, and Michael Fassbender in Austin, Texas; and Rebecca Hall, who starred in Nolan's 'The Prestige' and has a part in the upcoming 'Iron Man 3.'

All of these ladies sound like fine choices for the film, which begins production on March 4 and will hit theaters sometime in 2014.