Darren Aronofsky's portrait of addiction is captivating and deeply disturbing for many reasons. The film follows heroin addicts Harry (Jared Leto), his girlfriend Marion (Jennifer Connelly), and their friend Tyrone (Marlon Wayans) as they go deeper down the rabbit hole, becoming increasingly desperate to seek out their next high. We also watch as Harry's mother becomes addicted to weight loss pills in an attempt to return to the prime of her life so she can appear on an infomercial. Aronofsky takes ideas that seem so simple and non-threatening and turn them into weapons -- the recreational drug becomes an addiction, a televsion transforms from a lonely woman's best friend into her enemy, and a refrigerator takes on a life of its own. But the film's finale is notoriously hard to stomach, as we watch all four of our main characters reach the end of their rope in disgusting fashion. Once you see what Jennifer Connelly gets herself into just to score some dope, you'll never be the same.

More From ScreenCrush