The end is once again nigh for 'Futurama,' as this coming Wednesday will see the long-running sci-fi comedy blasting off one last time for its Comedy Central series finale "Meanwhile." We've heard this song and dance before, 'Futurama' having had two prior series finales to date, but does executive producer David X. Cohen believe Fry, Leela, Bender, Zoidberg and the rest of the Planet Express crew are really gone for good?

"In my heart I feel like it really is the end," says Cohen to TVGuide, adding that he'd been proven wrong on the matter before, though "Meanwhile" provides effective closure to the series. "Part of it is that the episode is so satisfying to me. It almost feels like we'd be wasting it if we came back again... But on the other hand, I'm reminded that I did say that with full conviction at least twice before, so people don't seem to believe me. My opinion has been shown to be not of much value in predicting the future on this one subject."

The finale itself will see the long-awaited nuptuials between Fry and Leela, though judging from what we've seen of the episode at Comic-Con 2013, plenty of sci-fi weirdness lies between the star-crossed lovers and the altar. Specifically, one of the Professor's new inventions will cause all manner of time distortions in the universe, on either side of those affected.

And while 'Futurama' may come to an ultimate close, there won't be lack for discussion as 'Talking Dead' host Chris Hardwick hosts two live online talk specials bidding farewell to the series with cast and crew, both before and after Wednesday's finale. We hate to say goodbye, though 'Futurama' will have certainly earned its rest this time.

What say you? Is 'Futurama' really gone for good this time, or could another network pick up where Comedy Central left off? Watch a preview from the final final series finale "Meanwhile" below, and give us your 'Futurama' hopes and dreams in the comments!