Break out the pills champagne, 'Nurse Jackie' fans!  Before the fourth season ends, you should know that your favorite pill-popping nurse will return for a fifth season!  It's not all good news however, as at least two names from behind the scenes won't return for a fifth year, instead being replaced by another Showtime vet.  But just what's going to happen to the show?

DeadlineTV is reporting that Edie Falco's acerbic recovering 'Nurse Jackie' has been renewed for a fifth season by Showtime, just two weeks shy of the series airing its fourth season finale.  However, current show-runners Linda Wallem and Liz Brixius are stepping down, leaving former 'Dexter' show-runner Clyde Phillips to take over beginning with season 5.

The reasoning behind the show-runner swap remains largely amicable, as Wallem and Brixius likely grew tired of working on a show that shot in New York from their home base of Los Angeles, much as the Connecticut-based Phillips left 'Dexter' for its L.A. production.  Considering 'Nurse Jackie's ratings have undergone a boost in its fourth season, Showtime boss David Nevins says of the news:

Clyde brings a unique combination of skills in both comedy and drama, and he is a master at making entertaining and compelling television.  We are so thrilled with the series’ performance this year, and we know that with the incomparable Edie Falco in front of the camera, the fifth season of Nurse Jackie will be even better.

What say you?  Will 'Nurse Jackie' still be 'Nurse Jackie' without its usual show-runners?  How have you been enjoying the fourth season?  Check out our recaps, and tell us what you think in the comments below!